1,2-Pentanediol (CAS 5343-92-0) — Citrus N/A Note Fragrance Ingredient

Citrus · Floral

1,_2-_Pentanediol

CAS 5343-92-0

Origin
synthetic
Note
N/A
IFRA
Generally safe
Data as of: Apr 2026

What Is 1,_2-_Pentanediol?

1,2-Pentanediol is a synthetic ingredient primarily used as a solvent or humectant in skincare products and some fragrances. You’ll find it in moisturizers, serums, and sometimes as part of fragrance delivery systems. While not a traditional perfumery ingredient, it plays a supporting role by helping blend other scent components and improving product texture.

Safety Profile

GENERALLY SAFE
Generally safeUse with awarenessProfessional use
Approved for cosmetic use worldwide
Low skin irritation potential
CAS
5343-92-0
Formula
Mixture
MW
Variable
Odor Family
Citrus · Floral
Layer 1 · Enthusiast

What Does 1,_2-_Pentanediol Smell Like?

1,2-Pentanediol is nearly odorless with just a faint, clean alcohol-like character. Its primary function isn’t olfactory but rather as a workhorse solvent that helps other fragrance ingredients blend smoothly. What subtle scent it does have disappears quickly when diluted, leaving no trace in the dry-down of formulations.

Layer 2

Chemistry, Properties & Perfumer Guide

The Chemistry

1,2-Pentanediol is a simple diol with five carbon atoms and hydroxyl groups at positions 1 and 2. As a synthetic material, it’s produced through controlled oxidation or reduction reactions of pentene derivatives. Its two hydroxyl groups make it water-soluble while the hydrocarbon backbone provides some organic solubility, making it useful as a bridge between polar and non-polar fragrance components.

Physical & Chemical Properties

Perfumer Guide

Note Position
N/A
Volatility
N/A
Blending
Functional solvent
ApplicationTypical %RangeNotes
Functional Products1-5%Up to 10%Humectant and solvent
Fragrance Bases0.5-3%Up to 5%Carrier for other ingredients

Classic Accords

Tip: Use to modify solubility parameters when blending polar and non-polar fragrance materials.

Alternatives & Comparisons

1
Propylene Glycol CAS 57-55-6

Similar solvent properties with slightly lower viscosity

2
Butylene Glycol CAS 107-88-0

Comparable humectant with better moisture retention

Layer 3

Safety, Regulatory & Sustainability

⚠ Regulatory Disclaimer

General reference only. Consult current IFRA Standards Library before formulating.

IFRA Status

No IFRA restrictions apply to 1,2-pentanediol.

RIFM Assessment

Considered safe for current fragrance uses by RIFM standards.

Sustainability

As a petrochemical-derived material, 1,2-pentanediol has moderate environmental impact from production. However, its high efficiency means relatively small quantities are needed in formulations. Some bio-based production routes are being explored to improve sustainability.

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References

    Data: PubChem (NIH), PubMed, RIFM, IFRA. Last reviewed: Apr 2026.

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