3-(4-Methyl-3-pentenyl)cyclohex-3-ene-1-carbaldehyde (CAS 52475-89-5) — Green Middle Note Fragrance Ingredient

Green · Citrus

3-(4-Methyl-3-pentenyl)cyclohex-3-ene-1-carbaldehyde

CAS 52475-89-5

Origin
synthetic
Note
Middle
IFRA
Use with awareness
Data as of: Apr 2026

What Is 3-(4-Methyl-3-pentenyl)cyclohex-3-ene-1-carbaldehyde?

3-(4-Methyl-3-pentenyl)cyclohex-3-ene-1-carbaldehyde is a synthetic fragrance ingredient used in perfumery. It’s found in various consumer products like fine fragrances and personal care items. This aldehyde contributes unique olfactory properties that enhance modern scent compositions.

Safety Profile

USE WITH AWARENESS
Generally safeUse with awarenessProfessional use
Approved for fragrance use
Potential sensitizer – follow IFRA guidelines
CAS
52475-89-5
Formula
Mixture
MW
Variable
Odor Family
Green · Citrus
Layer 1 · Enthusiast

What Does 3-(4-Methyl-3-pentenyl)cyclohex-3-ene-1-carbaldehyde Smell Like?

This aldehyde delivers a complex olfactory profile with green, citrusy top notes that evolve into a woody, slightly floral heart. The dry-down reveals subtle balsamic undertones with a clean, modern character. Its scent resembles crushed leaves with a hint of citrus peel, transitioning to a soft woody-amber background.

Scent Profile
Layer 2

2D Molecular Structure

3-(4-Methyl-3-penten-1-yl)-3-cyclohexene-1-carbaldehyde

SMILES: CC(C)=CCCC1=CCCC(C1)C=O

Chemistry, Properties & Perfumer Guide

The Chemistry

3-(4-Methyl-3-pentenyl)cyclohex-3-ene-1-carbaldehyde belongs to the class of unsaturated aldehydes. It’s synthesized through Diels-Alder reactions or oxidation of corresponding alcohols. The molecule features both cyclohexene and isoprenoid structural elements, contributing to its unique olfactory properties. The conjugated system influences its reactivity and scent characteristics.

Physical & Chemical Properties

Perfumer Guide

Note Position
Middle
Volatility
Medium (2-4 hours)
Blending
Good
ApplicationTypical %RangeNotes
Fine Fragrance1-3%Up to 5%Used as green-modifier
Personal Care0.5-1%Up to 2%Provides freshness

Classic Accords

Tip: Use in trace amounts to add green complexity without overwhelming the composition.

Alternatives & Comparisons

1
Cyclamen aldehyde CAS 103-95-7

Offers similar green floral character with better stability in alkaline formulations.

2
Triplal CAS 68039-49-6

Provides sharper green leaf notes for more pronounced vegetal effects.

Layer 3

Safety, Regulatory & Sustainability

⚠ Regulatory Disclaimer

General reference only. Consult current IFRA Standards Library before formulating.

IFRA Status

No specific IFRA restrictions. General aldehyde precautions apply.

RIFM Assessment

Limited safety data available. Recommended to use within standard fragrance industry guidelines.

Sustainability

As a synthetic material, this aldehyde offers consistent quality and reduces pressure on natural resources. Production can be optimized for minimal environmental impact through green chemistry principles.

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References

    Data: PubChem (NIH), PubMed, RIFM, IFRA. Last reviewed: Apr 2026.

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    Ingredient Data Sheet

    CAS 52475-89-5

    Physical Properties

    Molecular Weight192.3 g/mol🔬 PubChem
    LogP (Octanol-Water)3🔬 PubChem
    Boiling Point254 °C🔬 EPA CompTox
    Vapor Pressure0.1549 mmHg @ 25°C📊 OPERA
    Flash Point96.1 °C🔬 EPA CompTox
    Involatility Index0.012💻 Calculated
    log Kp (skin permeability)-1.743💻 Calculated
    SMILESCC(=CCCC1=CCCC(C1)C=O)C🔬 PubChem

    Volatility & Performance

    Fragrance NoteHeart💻 Calculated
    Volatility ClassSlow💻 Calculated
    Persistence Score1.5 / 5💻 Calculated

    Odor & Flavor

    Functional Groupsaldehydealkene💻 RDKit
    Data Sources & Attribution
    Physical data: PubChem (NIH/NLM), U.S. EPA CompTox Dashboard, EPA OPERA models, RDKit. Odor & flavor: Arctander (Perfume & Flavor Chemicals), Fenaroli's Handbook of Flavor Ingredients, Leffingwell. Thresholds: van Gemert (Compilations of Odour Threshold Values). Regulatory: IFRA Standards 51st, FEMA GRAS. Trade names: Surburg (Common Fragrance & Flavor Materials). All data compiled and cross-referenced for perfumertools.com.

    Physicochemical Properties

    DTXSID: DTXSID1052161

    Physical Properties

    Molecular Weight 192.302 g/mol🔬 EPA CompTox
    Density 0.933 g/cm^3📊 OPERA
    Boiling Point 263.245 °C📊 OPERA
    Melting Point 11.378 °C📊 OPERA
    Flash Point 109.999 °C📊 OPERA
    Refractive Index 1.524 Dimensionless📊 OPERA
    Molar Volume 201.331 cm^3/mol📊 OPERA

    Partition & Solubility

    LogP (Octanol-Water) 3.977 Log10 unitless📊 OPERA
    LogD (pH 5.5) 3.977 Log10 unitless📊 OPERA
    LogD (pH 7.4) 3.977 Log10 unitless📊 OPERA
    LogKoa (Octanol-Air) 6.9 Log10 unitless📊 OPERA
    Water Solubility 0.002 mol/L📊 OPERA
    Henry's Law Constant 0 atm-m3/mole📊 OPERA

    Transport Properties

    Vapor Pressure 0.055 mmHg📊 OPERA
    Viscosity 3.597 cP📊 OPERA
    Surface Tension 32.133 dyn/cm📊 OPERA
    Thermal Conductivity 135.952 mW/(m*K)📊 OPERA

    Molecular Descriptors

    Topological Polar Surface Area 17.07 Ų💻 Computed
    H-Bond Donors 0 count💻 Computed
    H-Bond Acceptors 1 count💻 Computed
    Rotatable Bonds 4 count💻 Computed
    Aromatic Rings 0 count💻 Computed
    Molar Refractivity 61.638 cm^3/mol📊 OPERA
    Polarizability 24.435 Å^3📊 OPERA

    Data Sources:

    🔬 EPA Experimental data from U.S. EPA CompTox Chemicals Dashboard & CTX APIs. 📊 OPERA Predicted using EPA's OPERA QSAR models. 💻 Computed Calculated from SMILES using RDKit.

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