4-(Isopropyl)-.beta.-methylcyclohexanethanol (CAS 67634-03-01) — Woody Base Note Fragrance Ingredient
4-(Isopropyl)-.beta.-methylcyclohexanethanol
CAS 67634-03-01
What Is 4-(Isopropyl)-.beta.-methylcyclohexanethanol?
4-(Isopropyl)-β-methylcyclohexanethanol is a synthetic aroma chemical used to add woody, musky, and slightly floral nuances to fragrances. Commonly found in masculine colognes and fabric softeners. It provides longevity and depth to scent compositions, making it valuable for creating sophisticated base notes.
Safety Profile
GENERALLY SAFEWhat Does 4-(Isopropyl)-.beta.-methylcyclohexanethanol Smell Like?
This molecule offers a complex olfactory profile: initial woody-amber tones reminiscent of aged cedar chests, evolving into a smooth musky heart with subtle floral undertones like dried rose petals. The dry-down reveals a clean, slightly powdery finish akin to well-worn leather. Its tenacity makes it ideal for anchoring fragrances.
In Famous Fragrances
Fragrance associations may not reflect actual formulations.
Used to enhance the woody-amber base, providing a modern interpretation of traditional masculine accords.
Contributes to the sophisticated woody-musky dry-down, complementing the citrus top notes.
Chemistry, Properties & Perfumer Guide
The Chemistry
4-(Isopropyl)-β-methylcyclohexanethanol is a synthetic terpenoid alcohol. It is typically produced through hydrogenation of corresponding ketones or via Grignard reactions. The isopropyl and methyl groups create steric hindrance, influencing its odor characteristics and volatility.
Physical & Chemical Properties
| Boiling Point | N/A |
|---|---|
| Density | N/A |
Perfumer Guide
| Application | Typical % | Range | Notes |
|---|---|---|---|
| Fine Fragrance | 1-5% | Up to 10% | Adds depth and longevity |
| Functional Fragrances | 0.5-3% | Up to 5% | Used in detergents and fabric softeners |
Classic Accords
Tip: Use in conjunction with musks and woods to enhance diffusion and tenacity.
Alternatives & Comparisons
Safety, Regulatory & Sustainability
⚠ Regulatory Disclaimer
General reference only. Consult current IFRA Standards Library before formulating.
IFRA Status
No IFRA restrictions currently apply.
RIFM Assessment
RIFM has assessed this material as safe for current use levels.
Sustainability
Synthesized from petrochemical precursors, this material has a moderate environmental footprint. Efforts are underway to develop greener synthetic routes using bio-based feedstocks.
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References
Data: PubChem (NIH), PubMed, RIFM, IFRA. Last reviewed: Apr 2026.
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