4-(Isopropyl)-.beta.-methylcyclohexanethanol (CAS 67634-03-01) — Woody Base Note Fragrance Ingredient

Woody · Musky

4-(Isopropyl)-.beta.-methylcyclohexanethanol

CAS 67634-03-01

Origin
synthetic
Note
Base
IFRA
Generally safe
Data as of: Apr 2026

What Is 4-(Isopropyl)-.beta.-methylcyclohexanethanol?

4-(Isopropyl)-β-methylcyclohexanethanol is a synthetic aroma chemical used to add woody, musky, and slightly floral nuances to fragrances. Commonly found in masculine colognes and fabric softeners. It provides longevity and depth to scent compositions, making it valuable for creating sophisticated base notes.

Safety Profile

GENERALLY SAFE
Generally safeUse with awarenessProfessional use
Safe in regulated products
Check for skin sensitivity
CAS
67634-03-01
Formula
Mixture
MW
Variable
Odor Family
Woody · Musky
Layer 1 · Enthusiast

What Does 4-(Isopropyl)-.beta.-methylcyclohexanethanol Smell Like?

This molecule offers a complex olfactory profile: initial woody-amber tones reminiscent of aged cedar chests, evolving into a smooth musky heart with subtle floral undertones like dried rose petals. The dry-down reveals a clean, slightly powdery finish akin to well-worn leather. Its tenacity makes it ideal for anchoring fragrances.

Scent Profile

In Famous Fragrances

Fragrance associations may not reflect actual formulations.

Sauvage(Dior, 2015)

Used to enhance the woody-amber base, providing a modern interpretation of traditional masculine accords.

Bleu de Chanel(Chanel, 2010)

Contributes to the sophisticated woody-musky dry-down, complementing the citrus top notes.

Layer 2

Chemistry, Properties & Perfumer Guide

The Chemistry

4-(Isopropyl)-β-methylcyclohexanethanol is a synthetic terpenoid alcohol. It is typically produced through hydrogenation of corresponding ketones or via Grignard reactions. The isopropyl and methyl groups create steric hindrance, influencing its odor characteristics and volatility.

Physical & Chemical Properties

Boiling PointN/A
DensityN/A

Perfumer Guide

Note Position
Base
Volatility
Low (hours-days)
Blending
Good
ApplicationTypical %RangeNotes
Fine Fragrance1-5%Up to 10%Adds depth and longevity
Functional Fragrances0.5-3%Up to 5%Used in detergents and fabric softeners

Classic Accords

Tip: Use in conjunction with musks and woods to enhance diffusion and tenacity.

Alternatives & Comparisons

1
Iso E Super CAS 54464-57-2

Offers similar woody characteristics but with more transparency and lift.

2
Timberol CAS 28219-61-6

Provides a more pronounced woody-amber effect with less muskiness.

Layer 3

Safety, Regulatory & Sustainability

⚠ Regulatory Disclaimer

General reference only. Consult current IFRA Standards Library before formulating.

IFRA Status

No IFRA restrictions currently apply.

RIFM Assessment

RIFM has assessed this material as safe for current use levels.

Sustainability

Synthesized from petrochemical precursors, this material has a moderate environmental footprint. Efforts are underway to develop greener synthetic routes using bio-based feedstocks.

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References

  1. PubChem PubChem
  2. IFRA Standards IFRA

Data: PubChem (NIH), PubMed, RIFM, IFRA. Last reviewed: Apr 2026.

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