Isononyl acetate (isomer unspecified) (CAS 40379-24-6) — Citrus Top Note Fragrance Ingredient

Citrus · Sweet

Isononyl acetate (isomer unspecified)

CAS 40379-24-6

Origin
synthetic
Note
Top
IFRA
Generally safe
Data as of: Apr 2026

What Is Isononyl acetate (isomer unspecified)?

Isononyl acetate is a synthetic fragrance ingredient rarely encountered by name, but sometimes used in consumer products for its fruity, slightly floral scent. It helps create fresh, modern fruit impressions in body care and household products. While not a major fragrance player, it contributes subtle nuance in formulations where its clean volatility is useful.

Safety Profile

GENERALLY SAFE
Generally safeUse with awarenessProfessional use
No major restrictions in current standards
Limited safety data – use moderate concentrations
CAS
40379-24-6
Formula
Mixture
MW
Variable
Odor Family
Citrus · Sweet
Layer 1 · Enthusiast

What Does Isononyl acetate (isomer unspecified) Smell Like?

Isononyl acetate presents a crisp, slightly green fruity character reminiscent of underripe pears or apple skins, with a subtle floral undertone. The top note is sharp and diffusive, quickly giving way to a cleaner mid-phase that blends well with citrus and light floral notes. It lacks significant base character, fading cleanly without heavy residue. The overall effect is a transparent, modern fruit impression that avoids candy-like sweetness.

Scent Profile
Layer 2

2D Molecular Structure

Acetic acid, isononyl ester

SMILES: CC(C)CCCCCCOC(C)=O

Chemistry, Properties & Perfumer Guide

The Chemistry

Isononyl acetate is a branched-chain ester formed by the reaction of acetic acid with isononanol. As an acetate ester, it belongs to a class known for fruity volatiles, though its branched structure gives it a cleaner profile than linear chain analogs. Industrial synthesis typically involves acid-catalyzed esterification. The unspecified isomer mixture means commercial material contains varying proportions of branched nonyl isomers, affecting exact olfactory properties.

Physical & Chemical Properties

Boiling PointNot well documented
DensityApprox. 0.86-0.88 g/cm³ (estimated)

Perfumer Guide

Note Position
Top
Volatility
Very high (<30 min)
Blending
Fair
ApplicationTypical %RangeNotes
Fine Fragrance0.1-1%Up to 3%Background fruit modifier
Functional Fragrance0.5-5%Up to 8%Fresh top note component

Classic Accords

Tip: Use to extend citrus top notes without adding excessive sweetness.

Alternatives & Comparisons

1
Nonyl acetate CAS 143-13-5

Linear chain version with stronger fruity character, more pear-like but less clean dry-down.

2
Isoamyl acetate CAS 123-92-2

Shorter chain ester with more pronounced banana note, higher impact but less sophistication.

Layer 3

Safety, Regulatory & Sustainability

⚠ Regulatory Disclaimer

General reference only. Consult current IFRA Standards Library before formulating.

IFRA Status

No IFRA restrictions as of Amendment 51 (2023).

RIFM Assessment

Not currently evaluated by RIFM due to limited commercial use.

Sustainability

Synthetic production from petrochemical feedstocks makes this a non-renewable material. No known major ecological hazards from production or use. Biodegradability expected to be moderate based on ester structure, but specific data lacking.

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References

  1. PubChem Compound Summary (2023). Isononyl acetate. PubChem
  2. Bauer et al. (2001). Common Fragrance and Flavor Materials.

Data: PubChem (NIH), PubMed, RIFM, IFRA. Last reviewed: Apr 2026.

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Perfumer’s Notes

Odor: [‘fruity’, ‘orris’, ‘woody’]

MW: 186.29

LogP: 3.5

Ingredient Data Sheet

CAS 40379-24-6

Physical Properties

Molecular Weight186.29 g/mol🔬 PubChem
LogP (Octanol-Water)3.5🔬 PubChem
Boiling Point220.8 °C🔬 EPA CompTox
Vapor Pressure0.1288 mmHg @ 25°C📊 OPERA
Flash Point82.9 °C🔬 EPA CompTox
Involatility Index0.0102💻 Calculated
log Kp (skin permeability)-1.351💻 Calculated

Volatility & Performance

Fragrance NoteHeart💻 Calculated
Volatility ClassSlow💻 Calculated
Persistence Score1.7 / 5💻 Calculated

Odor & Flavor

Primary Descriptorsfruityorriswoody• leffingwell
Data Sources & Attribution
Physical data: PubChem (NIH/NLM), U.S. EPA CompTox Dashboard, EPA OPERA models, RDKit. Odor & flavor: Arctander (Perfume & Flavor Chemicals), Fenaroli's Handbook of Flavor Ingredients, Leffingwell. Thresholds: van Gemert (Compilations of Odour Threshold Values). Regulatory: IFRA Standards 51st, FEMA GRAS. Trade names: Surburg (Common Fragrance & Flavor Materials). All data compiled and cross-referenced for perfumertools.com.

Physicochemical Properties

DTXSID: DTXSID4041577

Physical Properties

Molecular Weight 186.295 g/mol🔬 EPA CompTox
Density 0.873 g/cm^3🔬 EPA CTX
Boiling Point 220.8 °C🔬 EPA CTX
Melting Point -26 °C🔬 EPA CTX
Flash Point 83.781 °C📊 OPERA
Refractive Index 1.425 Dimensionless📊 OPERA
Molar Volume 213.969 cm^3/mol📊 OPERA

Partition & Solubility

LogP (Octanol-Water) 4.222 Log10 unitless📊 OPERA
LogD (pH 5.5) 4.222 Log10 unitless📊 OPERA
LogD (pH 7.4) 4.222 Log10 unitless📊 OPERA
LogKoa (Octanol-Air) 5.56 Log10 unitless📊 OPERA
Water Solubility 0.001 mol/L📊 OPERA
Henry's Law Constant 0 atm-m3/mole📊 OPERA

Transport Properties

Vapor Pressure 0.125 mmHg📊 OPERA
Viscosity 1.828 cP📊 OPERA
Surface Tension 27.235 dyn/cm📊 OPERA
Thermal Conductivity 136.091 mW/(m*K)📊 OPERA

Molecular Descriptors

Topological Polar Surface Area 26.3 Ų💻 Computed
H-Bond Donors 0 count💻 Computed
H-Bond Acceptors 2 count💻 Computed
Rotatable Bonds 7 count💻 Computed
Aromatic Rings 0 count💻 Computed
Molar Refractivity 54.744 cm^3/mol📊 OPERA
Polarizability 21.702 Å^3📊 OPERA

Data Sources:

🔬 EPA Experimental data from U.S. EPA CompTox Chemicals Dashboard & CTX APIs. 📊 OPERA Predicted using EPA's OPERA QSAR models. 💻 Computed Calculated from SMILES using RDKit.

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