Isotridecan-1-ol (CAS 27458-92-0) — Woody Base Note Fragrance Ingredient

ByThe Good Scents
Woody · Balsamic

Isotridecan-1-ol

CAS 27458-92-0

Origin
synthetic
Note
Base
IFRA
Generally safe
Data as of: Apr 2026

What Is Isotridecan-1-ol?

Isotridecan-1-ol is a synthetic alcohol used primarily as a fixative in functional fragrances like detergents and cleaning products. You won’t find it in fine perfumery, but it helps stabilize scents in household items. This ingredient matters because it extends the lifespan of functional fragrances, ensuring your laundry or surfaces retain their fresh scent longer between washes or cleanings.

Safety Profile

GENERALLY SAFE
Generally safeUse with awarenessProfessional use
✓ Approved for use in consumer products
⚠ Avoid direct skin contact in concentrated form
CAS
27458-92-0
Formula
Mixture
MW
Variable
Odor Family
Woody · Balsamic
Layer 1 · Enthusiast

What Does Isotridecan-1-ol Smell Like?

Isotridecan-1-ol has a faint, waxy-alcoholic odor that serves primarily as a functional base rather than a distinctive scent. Its odor profile is neutral and clean, with subtle fatty undertones reminiscent of candle wax. In formulations, it acts as an invisible backbone, helping to anchor more volatile top notes without contributing significant character of its own.

Scent Profile
Layer 2

2D Molecular Structure

Isotridecanol

SMILES: CC(C)CCCCCCCCCCO

Chemistry, Properties & Perfumer Guide

The Chemistry

Isotridecan-1-ol is a branched-chain fatty alcohol with 13 carbon atoms. It’s produced industrially through hydroformylation of dodecene followed by hydrogenation. The ‘iso’ prefix indicates a branched molecular structure rather than a straight chain. This branching affects physical properties like melting point and solubility compared to its linear counterpart. As a higher alcohol, it’s less volatile than short-chain alcohols and shows good stability in alkaline formulations.

Physical & Chemical Properties

AppearanceColorless liquid
Boiling Point~250-280°C (estimated)
SolubilityLow water solubility, soluble in alcohols

Perfumer Guide

Note Position
Base
Volatility
Very low
Blending
Functional
ApplicationTypical %RangeNotes
Laundry Detergents0.5-2%Up to 5%Fragrance stabilizer
Household Cleaners0.1-1%Up to 3%Scent longevity
Industrial Fragrances1-3%Up to 8%Base note fixative

Classic Accords

Tip: Use as a neutral backbone in functional fragrances where scent longevity is more important than olfactory character.

Alternatives & Comparisons

1
Tetradecan-1-ol CAS 112-72-1

Similar function with slightly higher molecular weight and lower volatility.

2
Dodecan-1-ol CAS 112-53-8

Shorter chain length alternative when less fixation is needed.

Layer 3

Safety, Regulatory & Sustainability

⚠ Regulatory Disclaimer

General reference only. Consult current IFRA Standards Library before formulating.

IFRA Status

No IFRA restrictions apply to isotridecan-1-ol.

RIFM Assessment

Not currently evaluated by RIFM due to industrial rather than fine fragrance use.

Sustainability

As a petrochemical derivative, isotridecan-1-ol has significant carbon footprint from production. However, its effectiveness at low concentrations mitigates some environmental impact. No known bio-based alternatives exist at commercial scale. Proper disposal through wastewater systems is acceptable due to biodegradability.

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References

    Data: PubChem (NIH), PubMed, RIFM, IFRA. Last reviewed: Apr 2026.

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    Perfumer’s Notes

    MW: 200.36

    LogP: 5.4

    Ingredient Data Sheet

    CAS 27458-92-0

    Physical Properties

    Molecular Weight200.36 g/mol🔬 PubChem
    LogP (Octanol-Water)5.4🔬 PubChem
    log Kp (skin permeability)-0.088💻 Calculated
    SMILESCC(C)CCCCCCCCCCO🔬 PubChem

    Odor & Flavor

    Functional Groupsalcohol💻 RDKit
    Data Sources & Attribution
    Physical data: PubChem (NIH/NLM), U.S. EPA CompTox Dashboard, EPA OPERA models, RDKit. Odor & flavor: Arctander (Perfume & Flavor Chemicals), Fenaroli's Handbook of Flavor Ingredients, Leffingwell. Thresholds: van Gemert (Compilations of Odour Threshold Values). Regulatory: IFRA Standards 51st, FEMA GRAS. Trade names: Surburg (Common Fragrance & Flavor Materials). All data compiled and cross-referenced for perfumertools.com.

    Physicochemical Properties

    DTXSID: DTXSID1029752

    Physical Properties

    Molecular Weight 200.36 g/mol🔬 PubChem

    Partition & Solubility

    LogP (Octanol-Water) 5.4 Log10 unitless🔬 PubChem

    Molecular Descriptors

    Topological Polar Surface Area 20.23 Ų💻 Computed
    H-Bond Donors 1 count💻 Computed
    H-Bond Acceptors 1 count💻 Computed
    Rotatable Bonds 10 count💻 Computed
    Molar Refractivity 63.48 cm^3/mol💻 Computed

    Data Sources:

    🔬 EPA Experimental data from U.S. EPA CompTox Chemicals Dashboard & CTX APIs. 📊 OPERA Predicted using EPA's OPERA QSAR models. 💻 Computed Calculated from SMILES using RDKit.

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