Methyl decenone (CAS 811412-48-3) — Sweet Top to heart Note Fragrance Ingredient

Sweet · Floral

Methyl decenone

CAS 811412-48-3

Origin
synthetic
Note
Top to heart
IFRA
Generally safe
Data as of: Apr 2026

What Is Methyl decenone?

Methyl decenone is a synthetic fragrance ingredient used to add fruity, floral, and slightly woody nuances to perfumes. You’ll encounter it in modern floral and fruity fragrances, often as part of the top or heart notes. This molecule matters because it provides a unique balance between freshness and depth, helping perfumers create contemporary scent profiles that evolve beautifully on skin.

Safety Profile

GENERALLY SAFE
Generally safeUse with awarenessProfessional use
No major restrictions
Always patch test new formulations
CAS
811412-48-3
Formula
Mixture
MW
Variable
Odor Family
Sweet · Floral
Layer 1 · Enthusiast

What Does Methyl decenone Smell Like?

Methyl decenone opens with a burst of juicy pear and ripe melon, quickly revealing a floral heart reminiscent of jasmine petals dipped in honey. As it dries down, the sweetness mellows into a sophisticated woody-musky base with hints of clean cotton. The evolution is remarkably smooth, transitioning from fruity freshness to a skin-hugging warmth that lasts for hours. Imagine biting into a perfectly ripe peach while walking through a sun-dappled orchard – that’s the olfactory journey this molecule creates.

Scent Profile

In Famous Fragrances

Fragrance associations may not reflect actual formulations.

J'adore(Dior, 1999)

Used here to amplify the floral bouquet while adding a modern fruity twist that prevents the white flowers from becoming too heavy.

Light Blue(Dolce & Gabbana, 2001)

Provides the juicy apple-pear top note that makes this fragrance instantly recognizable and refreshing.

Layer 2

2D Molecular Structure

(3E)-4-Methyl-3-decen-5-one

SMILES: CCCCCC(=O)C(\C)=C\CC

Chemistry, Properties & Perfumer Guide

The Chemistry

Methyl decenone belongs to the ketone family, specifically a methyl-substituted decenone. As a synthetic molecule, it’s produced through controlled organic synthesis routes, typically involving condensation reactions of appropriate precursors. The specific stereochemistry contributes to its odor profile – the E-isomer tends to be fruitier while the Z-isomer leans more floral.

Physical & Chemical Properties

AppearanceColorless to pale yellow liquid
SolubilitySoluble in alcohol and oils

Perfumer Guide

Note Position
Top to heart
Volatility
Medium (2-4 hours)
Blending
Very good
ApplicationTypical %RangeNotes
Fine Fragrance1-3%0.5-5%Adds fruity-floral lift
Body Care0.1-0.5%Up to 1%Provides fresh character

Classic Accords

+ Hedione + Galaxolide = Modern floral + Ethyl Maltol + Vanillin = Fruity gourmand

Tip: Use with citrus top notes to create sparkling fruity openings that transition smoothly into floral hearts.

Alternatives & Comparisons

1
Methyl dihydrojasmonate CAS 24851-98-7

For a more floral, less fruity character with similar longevity.

Layer 3

Safety, Regulatory & Sustainability

⚠ Regulatory Disclaimer

General reference only. Consult current IFRA Standards Library before formulating.

IFRA Status

Not currently restricted by IFRA standards.

RIFM Assessment

Considered safe at current usage levels based on available data.

Sustainability

As a synthetic material, methyl decenone has minimal environmental impact in production compared to some natural alternatives. Its consistent quality reduces batch-to-batch variation and waste in formulation.

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References

  1. Bauer et al. (2001). Common Fragrance and Flavor Materials. Wiley-VCH.

Data: PubChem (NIH), PubMed, RIFM, IFRA. Last reviewed: Apr 2026.

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Ingredient Data Sheet

CAS 811412-48-3

Physical Properties

Molecular Weight168.28 g/mol🔬 PubChem
LogP (Octanol-Water)3.5🔬 PubChem
Boiling Point220 °C🔬 EPA CompTox
Vapor Pressure0.2291 mmHg @ 25°C📊 OPERA
Flash Point97 °C🔬 EPA CompTox
Involatility Index0.019💻 Calculated
log Kp (skin permeability)-1.242💻 Calculated
SMILESCCCCCC(=O)C(=CCC)C🔬 PubChem

Volatility & Performance

Fragrance NoteHeart💻 Calculated
Volatility ClassSlow💻 Calculated
Persistence Score1.2 / 5💻 Calculated

Odor & Flavor

Primary Descriptorsfloralsweet• leffingwell
Functional Groupsketonealkene💻 RDKit
Data Sources & Attribution
Physical data: PubChem (NIH/NLM), U.S. EPA CompTox Dashboard, EPA OPERA models, RDKit. Odor & flavor: Arctander (Perfume & Flavor Chemicals), Fenaroli's Handbook of Flavor Ingredients, Leffingwell. Thresholds: van Gemert (Compilations of Odour Threshold Values). Regulatory: IFRA Standards 51st, FEMA GRAS. Trade names: Surburg (Common Fragrance & Flavor Materials). All data compiled and cross-referenced for perfumertools.com.

Physicochemical Properties

DTXSID: DTXSID70889208

Physical Properties

Molecular Weight 168.28 g/mol🔬 EPA CompTox
Density 0.857 g/cm^3📊 OPERA
Boiling Point 230.045 °C📊 OPERA
Melting Point 5.117 °C📊 OPERA
Flash Point 97.691 °C📊 OPERA
Refractive Index 1.441 Dimensionless📊 OPERA
Molar Volume 200.646 cm^3/mol📊 OPERA

Partition & Solubility

LogP (Octanol-Water) 3.86 Log10 unitless📊 OPERA
LogD (pH 5.5) 3.86 Log10 unitless📊 OPERA
LogD (pH 7.4) 3.86 Log10 unitless📊 OPERA
LogKoa (Octanol-Air) 6.29 Log10 unitless📊 OPERA
Water Solubility 0.001 mol/L📊 OPERA
Henry's Law Constant 0 atm-m3/mole📊 OPERA

Transport Properties

Vapor Pressure 0.114 mmHg📊 OPERA
Surface Tension 28.698 dyn/cm📊 OPERA

Molecular Descriptors

Topological Polar Surface Area 17.07 Ų💻 Computed
H-Bond Donors 0 count💻 Computed
H-Bond Acceptors 1 count💻 Computed
Rotatable Bonds 6 count💻 Computed
Aromatic Rings 0 count💻 Computed
Molar Refractivity 52.941 cm^3/mol📊 OPERA
Polarizability 20.987 Å^3📊 OPERA

Data Sources:

🔬 EPA Experimental data from U.S. EPA CompTox Chemicals Dashboard & CTX APIs. 📊 OPERA Predicted using EPA's OPERA QSAR models. 💻 Computed Calculated from SMILES using RDKit.

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