Pyrazine, 2-methoxy-3-propyl- (CAS 25680-57-3) — Green Top to middle Note Fragrance Ingredient
Pyrazine, 2-methoxy-3-propyl-
CAS 25680-57-3
What Is Pyrazine, 2-methoxy-3-propyl-?
2-Methoxy-3-propylpyrazine is a synthetic aroma chemical found in perfumes and some food flavorings. It contributes a green, bell pepper-like note to fragrances. This ingredient matters because it provides a crisp, vegetal character that perfumers use to create naturalistic green accords or to add dimension to floral compositions.
Safety Profile
USE WITH AWARENESSWhat Does Pyrazine, 2-methoxy-3-propyl- Smell Like?
This pyrazine derivative delivers an intensely green, vegetal aroma reminiscent of freshly cut bell peppers with a subtle earthy undertone. The initial burst is sharp and slightly metallic, evolving into a more rounded green character that persists in the heart phase. In dry-down, it leaves a faint earthy trace that blends well with woody bases. The effect is like walking through a dewy vegetable garden at dawn – crisp, slightly damp, and alive with chlorophyll-rich vibrancy.
Chemistry, Properties & Perfumer Guide
The Chemistry
2-Methoxy-3-propylpyrazine belongs to the alkylmethoxypyrazine class of heterocyclic compounds, known for their potent aroma characteristics. These molecules are typically synthesized through condensation reactions starting from diketones and diamines, followed by selective alkylation. The methoxy and propyl substituents at positions 2 and 3 respectively create its distinctive green odor profile. While pyrazines occur naturally in some vegetables, this specific compound is primarily produced synthetically for fragrance applications due to its stability and consistent quality.
Physical & Chemical Properties
| Appearance | Colorless to pale yellow liquid |
|---|---|
| Odor Type | Green, vegetal |
Perfumer Guide
| Application | Typical % | Range | Notes |
|---|---|---|---|
| Fine Fragrance | 0.1-0.5% | Up to 1% | Used as green modifier |
| Functional Fragrance | 0.01-0.1% | Up to 0.3% | For fresh accents |
Classic Accords
Tip: Use in trace amounts to avoid overpowering other notes.
Alternatives & Comparisons
More intense bell pepper character, used when a stronger green note is desired.
Safety, Regulatory & Sustainability
⚠ Regulatory Disclaimer
General reference only. Consult current IFRA Standards Library before formulating.
IFRA Status
No current IFRA restrictions. Listed as safe when used within standard industry guidelines.
RIFM Assessment
RIFM assessment confirms safe use at current industry levels.
Sustainability
As a synthetic material, 2-methoxy-3-propylpyrazine offers consistent quality without agricultural impacts. Production follows standard petrochemical routes with typical industry controls for waste management. Its high potency means very small quantities are needed, reducing overall environmental load compared to some natural extracts with similar odor profiles.
Explore Pyrazine, 2-methoxy-3-propyl-
Browse essential oils and aroma compounds.
Browse on iHerb →Affiliate disclosure: we may earn a small commission at no extra cost to you.
Related Research
- Vetiverol acetate, distilled (CAS 73246-97-6) — Woody Base Note Fragrance Ingredient
- 8-Undecenal (CAS 58296-81-4) — Citrus Top Note Fragrance Ingredient
- Bis(hydroxymethyl)tricyclo[5.2.1.02,6]decane (CAS 26160-83-8) — Woody Middle Note Fragrance Ingredient
- 1H-Indene, 2,3-dihydro-1,1,2,3,3-pentamethyl- (CAS 1203-17-4) — Woody Base Note Fragrance Ingredient
