Vanillyl ethyl ether (CAS 13184-86-6) — Sweet Heart to base Note Fragrance Ingredient
Vanillyl ethyl ether
CAS 13184-86-6
What Is Vanillyl ethyl ether?
Vanillyl ethyl ether is a synthetic fragrance ingredient that mimics the warm, creamy aspects of vanilla with added depth. You’ll find it in gourmand perfumes, candles, and body care products where a rich vanilla note is desired. This molecule matters because it provides superior stability compared to natural vanilla extracts, allowing fragrances to maintain their character without discoloration or rapid evaporation.
Safety Profile
GENERALLY SAFEWhat Does Vanillyl ethyl ether Smell Like?
Vanillyl ethyl ether unfolds like melted vanilla pod resin warmed over aged oak. The opening carries a sweet-dusty powderiness reminiscent of vanilla sugar, quickly deepening into a creamy balsamic heart with whispers of caramelized tonka bean. Unlike simpler vanillins, it develops a sophisticated woody-amber drydown that lingers close to skin, avoiding the cloying sweetness of some vanilla analogs. The ethyl ether modification adds an airy lift that prevents heaviness, making it ideal for modern gourmand compositions.
In Famous Fragrances
Fragrance associations may not reflect actual formulations.
Used here to create the illusion of aged vanilla extract in rum barrels, its etheric quality enhances the boozy top notes while preventing the base from becoming overly food-like.
Provides the creamy backbone that balances the saffron and coffee notes, its woody drydown connecting the gourmand elements to the sandalwood base.
Chemistry, Properties & Perfumer Guide
The Chemistry
Vanillyl ethyl ether is an aromatic ether derivative of vanillin, where the phenolic hydroxyl group is ethylated. This modification increases volatility and alters polarity compared to vanillin. Synthesized through Williamson ether synthesis from vanillin and ethyl halides, the ether linkage provides enhanced stability against oxidation. The molecule retains vanillin’s signature 4-hydroxy-3-methoxyphenyl motif but with altered hydrogen bonding capacity that affects both scent profile and solubility.
Physical & Chemical Properties
| Appearance | White to pale yellow crystalline powder |
|---|---|
| Solubility | Soluble in ethanol, propylene glycol; slightly soluble in water |
Perfumer Guide
| Application | Typical % | Range | Notes |
|---|---|---|---|
| Fine Fragrance | 0.5-3% | Up to 5% | Gourmand and oriental bases |
| Home Care | 0.1-1% | Up to 2% | Warm background note |
Classic Accords
Tip: Combine with ionones to create a ‘vanilla flower’ effect without excessive sweetness.
Alternatives & Comparisons
When a more straightforward vanilla note is needed, though it lacks the woody complexity of the ether derivative.
Safety, Regulatory & Sustainability
⚠ Regulatory Disclaimer
General reference only. Consult current IFRA Standards Library before formulating.
IFRA Status
No restrictions under IFRA standards.
RIFM Assessment
Recognized as safe for current usage levels in fragrance applications.
Sustainability
As a synthetic material, vanillyl ethyl ether avoids the supply chain issues and deforestation concerns associated with natural vanilla. Its production from guaiacol or lignin-derived vanillin can utilize renewable feedstocks. The molecule’s potency reduces required quantities compared to natural extracts.
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References
- Burdock, G.A. (2010). Fenaroli’s Handbook of Flavor Ingredients. CRC Press. ISBN 9781420090867
Data: PubChem (NIH), PubMed, RIFM, IFRA. Last reviewed: Apr 2026.
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